2y2b: Difference between revisions

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<StructureSection load='2y2b' size='340' side='right'caption='[[2y2b]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2y2b' size='340' side='right'caption='[[2y2b]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y2b]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y2B FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y2b]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y2B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AH0:2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC+ACID'>AH0</scene>, <scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AH0:2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC+ACID'>AH0</scene>, <scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j3g|1j3g]], [[2y2c|2y2c]], [[2y2d|2y2d]], [[2y2e|2y2e]], [[2y28|2y28]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acetylmuramoyl-L-alanine_amidase N-acetylmuramoyl-L-alanine amidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.28 3.5.1.28] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y2b OCA], [https://pdbe.org/2y2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y2b RCSB], [https://www.ebi.ac.uk/pdbsum/2y2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y2b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y2b OCA], [https://pdbe.org/2y2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y2b RCSB], [https://www.ebi.ac.uk/pdbsum/2y2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y2b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AMPD_CITFR AMPD_CITFR]] Involved in both cell wall peptidoglycans recycling and beta-lactamase induction. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety.  
[https://www.uniprot.org/uniprot/AMPD_CITFR AMPD_CITFR] Involved in both cell wall peptidoglycans recycling and beta-lactamase induction. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterium freundii braak 1928]]
[[Category: Citrobacter freundii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N-acetylmuramoyl-L-alanine amidase]]
[[Category: Andre I]]
[[Category: Andre, I]]
[[Category: Barbe S]]
[[Category: Barbe, S]]
[[Category: Carrasco-Lopez C]]
[[Category: Carrasco-Lopez, C]]
[[Category: Hermoso JA]]
[[Category: Hermoso, J A]]
[[Category: Hesek D]]
[[Category: Hesek, D]]
[[Category: Lee M]]
[[Category: Lee, M]]
[[Category: Martinez-Ripoll M]]
[[Category: Martinez-Ripoll, M]]
[[Category: Mobashery S]]
[[Category: Mobashery, S]]
[[Category: Rojas-Altuve A]]
[[Category: Rojas-Altuve, A]]
[[Category: Silva-Martin N]]
[[Category: Silva-Martin, N]]
[[Category: Zhang W]]
[[Category: Zhang, W]]
[[Category: Activation mechanism]]
[[Category: Amidase_2 family]]
[[Category: Hydrolase]]
[[Category: Peptidoglycan amidase]]
Retrieved from "https://proteopedia.org/2y2b"