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==Structure of the Schizosaccharomyces pombe Mediator subunit Med6==
==Structure of the Schizosaccharomyces pombe Mediator subunit Med6==
<StructureSection load='4h61' size='340' side='right' caption='[[4h61]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4h61' size='340' side='right'caption='[[4h61]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h61]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H61 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H61 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H61 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h62|4h62]], [[4h63|4h63]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h61 OCA], [https://pdbe.org/4h61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h61 RCSB], [https://www.ebi.ac.uk/pdbsum/4h61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h61 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">med6, pmc5, SPAC1002.15c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h61 OCA], [http://pdbe.org/4h61 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h61 RCSB], [http://www.ebi.ac.uk/pdbsum/4h61 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h61 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MED6_SCHPO MED6_SCHPO]] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  
[https://www.uniprot.org/uniprot/MED6_SCHPO MED6_SCHPO] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fission yeast]]
[[Category: Large Structures]]
[[Category: Cramer, P]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Kurth, F]]
[[Category: Cramer P]]
[[Category: Lariviere, L]]
[[Category: Kurth F]]
[[Category: Plaschka, C]]
[[Category: Lariviere L]]
[[Category: Seizl, M]]
[[Category: Plaschka C]]
[[Category: Wenzeck, L]]
[[Category: Seizl M]]
[[Category: Mediator complex]]
[[Category: Wenzeck L]]
[[Category: Nucleus]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/4h61"