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==Structural insights into the reduction mechanism of Saccharomyces cerevisia Riboflavin Biosynthesis Reductase Rib7==
==Structural insights into the reduction mechanism of Saccharomyces cerevisia Riboflavin Biosynthesis Reductase Rib7==
<StructureSection load='4ha7' size='340' side='right' caption='[[4ha7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4ha7' size='340' side='right'caption='[[4ha7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ha7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HA7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ha7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HA7 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ha9|4ha9]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ha7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ha7 OCA], [https://pdbe.org/4ha7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ha7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ha7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ha7 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIB7, YBR153W, YBR1203 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone_5'-phosphate_reductase 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.302 1.1.1.302] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ha7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ha7 OCA], [http://pdbe.org/4ha7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ha7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ha7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ha7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RIB7_YEAST RIB7_YEAST]] Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate (Probable).  
[https://www.uniprot.org/uniprot/RIB7_YEAST RIB7_YEAST] Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate (Probable).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Liu, Y]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Lv, Z]]
[[Category: Liu Y]]
[[Category: Sun, J]]
[[Category: Lv Z]]
[[Category: Nadph binding]]
[[Category: Sun J]]
[[Category: Oxidoreductase]]
[[Category: Reductase]]

Revision as of 08:06, 3 November 2022

Structural insights into the reduction mechanism of Saccharomyces cerevisia Riboflavin Biosynthesis Reductase Rib7

4ha7, resolution 2.10Å

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