4hd0: Difference between revisions
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==Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair== | ==Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair== | ||
<StructureSection load='4hd0' size='340' side='right' caption='[[4hd0]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4hd0' size='340' side='right'caption='[[4hd0]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4hd0]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4hd0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HD0 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hd0 OCA], [https://pdbe.org/4hd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hd0 RCSB], [https://www.ebi.ac.uk/pdbsum/4hd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hd0 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MRE11_PYRFU MRE11_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Kertokalio | [[Category: Pyrococcus furiosus DSM 3638]] | ||
[[Category: Limbo | [[Category: Kertokalio A]] | ||
[[Category: Moiani | [[Category: Limbo O]] | ||
[[Category: Russell | [[Category: Moiani D]] | ||
[[Category: Tainer | [[Category: Russell P]] | ||
[[Category: Wyman | [[Category: Tainer JA]] | ||
[[Category: Wyman C]] | |||