4ht1: Difference between revisions

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<StructureSection load='4ht1' size='340' side='right'caption='[[4ht1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4ht1' size='340' side='right'caption='[[4ht1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ht1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HT1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ht1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HT1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HT1 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ht1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ht1 OCA], [http://pdbe.org/4ht1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ht1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ht1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ht1 ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ht1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ht1 OCA], [https://pdbe.org/4ht1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ht1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ht1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ht1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TNF12_HUMAN TNF12_HUMAN]] Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.<ref>PMID:10085077</ref>
[https://www.uniprot.org/uniprot/TNF12_HUMAN TNF12_HUMAN] Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.<ref>PMID:10085077</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Tumor necrosis factor ligand superfamily|Tumor necrosis factor ligand superfamily]]
*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
*[[Tumor necrosis factor receptor|Tumor necrosis factor receptor]]
*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Lammens, A]]
[[Category: Lammens A]]
[[Category: Antibody fab]]
[[Category: Cytokine]]
[[Category: Extracellular thd domain]]
[[Category: Immune system]]
[[Category: Membrane bound]]
[[Category: Tnf homology domain]]
[[Category: Tweak receptor]]