4i0a: Difference between revisions

<StructureSection load='4i0a' size='340' side='right'caption='[[4i0a]], [[Resolution|resolution]] 2.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[4i0a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0A FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0a OCA], [https://pdbe.org/4i0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0a RCSB], [https://www.ebi.ac.uk/pdbsum/4i0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0a ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>  

*[[Catabolite gene activator protein 3D structures|Catabolite gene activator protein 3D structures]]

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: Burnell D]]

[[Category: Cann MJ]]

[[Category: McLeish TCB]]

[[Category: Pohl E]]

[[Category: Rodgers T]]

[[Category: Townsend PD]]

[[Category: Wilson MR]]