4i5q: Difference between revisions

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==Crystal structure and catalytic mechanism for peroplasmic disulfide-bond isomerase DsbC from Salmonella enterica serovar Typhimurium==
==Crystal structure and catalytic mechanism for peroplasmic disulfide-bond isomerase DsbC from Salmonella enterica serovar Typhimurium==
<StructureSection load='4i5q' size='340' side='right' caption='[[4i5q]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
<StructureSection load='4i5q' size='340' side='right'caption='[[4i5q]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4i5q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I5Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[4i5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I5Q FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dsbC, STM3043 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i5q OCA], [https://pdbe.org/4i5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i5q RCSB], [https://www.ebi.ac.uk/pdbsum/4i5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i5q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i5q OCA], [http://pdbe.org/4i5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i5q RCSB], [http://www.ebi.ac.uk/pdbsum/4i5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i5q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DSBC_SALTY DSBC_SALTY]] Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase.  
[https://www.uniprot.org/uniprot/DSBC_SALTY DSBC_SALTY] Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4i5q" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4i5q" style="background-color:#fffaf0;"></div>
==See Also==
*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Salty]]
[[Category: Large Structures]]
[[Category: Ha, N C]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Kim, J S]]
[[Category: Ha NC]]
[[Category: Lee, K]]
[[Category: Kim JS]]
[[Category: Li, J]]
[[Category: Lee K]]
[[Category: Yeom, J H]]
[[Category: Li J]]
[[Category: Yoon, B Y]]
[[Category: Yeom JH]]
[[Category: Cxxc motif]]
[[Category: Yoon BY]]
[[Category: Disuflide isomerase]]
[[Category: Isomerase]]
[[Category: Periplasmic]]