4i7w: Difference between revisions

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==Agrobacterium tumefaciens DHDPS with lysine and pyruvate==
==Agrobacterium tumefaciens DHDPS with lysine and pyruvate==
<StructureSection load='4i7w' size='340' side='right' caption='[[4i7w]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='4i7w' size='340' side='right'caption='[[4i7w]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4i7w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrsh Agrsh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I7W FirstGlance]. <br>
<table><tr><td colspan='2'>[[4i7w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabacearum Agrobacterium fabacearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I7W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7w OCA], [https://pdbe.org/4i7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i7w RCSB], [https://www.ebi.ac.uk/pdbsum/4i7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7w ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i7u|4i7u]], [[4i7v|4i7v]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapA, AGROH133_05014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=861208 AGRSH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i7w OCA], [http://pdbe.org/4i7w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i7w RCSB], [http://www.ebi.ac.uk/pdbsum/4i7w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i7w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/F0L8Z6_AGRSH F0L8Z6_AGRSH]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (By similarity).[HAMAP-Rule:MF_00418][SAAS:SAAS020625_004_011311]  
[https://www.uniprot.org/uniprot/F0L8Z6_AGRFH F0L8Z6_AGRFH] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[ARBA:ARBA00003294][HAMAP-Rule:MF_00418]


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
[[Category: Agrobacterium fabacearum]]
[[Category: Agrsh]]
[[Category: Large Structures]]
[[Category: Atkinson, S C]]
[[Category: Atkinson SC]]
[[Category: Dobson, R C.J]]
[[Category: Dobson RCJ]]
[[Category: Dogovski, C]]
[[Category: Dogovski C]]
[[Category: Perugini, M A]]
[[Category: Perugini MA]]
[[Category: Biosynthetic protein]]
[[Category: Cytosol]]
[[Category: Lysine biosynthesis]]
[[Category: Pyruvate bound to acitve site lysine]]
[[Category: Tim barrel]]
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