Sandbox Reserved 1735: Difference between revisions
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== Structural Highlights of HIV-1 | == Structural Highlights of HIV-1 protease== | ||
==Structural Highlights of HIV-2 | ==Structural Highlights of HIV-2 protease== | ||
== HIV-1 | == HIV-1 Protease in Humans== | ||
HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013). | HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013). | ||
==HIV-2 | ==HIV-2 Protease in Humans== | ||
==The role of CD4+ T-cell== | ==The role of CD4+ T-cell== | ||
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==HIV Prevention== | ==HIV Prevention== | ||
== References == | == References == | ||