7qun: Difference between revisions
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==CryoEM structure of mammalian AAP in complex with Meropenem== | |||
<StructureSection load='7qun' size='340' side='right'caption='[[7qun]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7qun]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa_domesticus Sus scrofa domesticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QUN FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DWZ:(2S,3R,4S)-4-{[(3S,5S)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-2-[(1S,2R)-1-FORMYL-2-HYDROXYPROPYL]-3-METHYL-3,4-DIHYDRO-2H-PYRROLE-5-CARBOXYLIC+ACID'>DWZ</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qun OCA], [https://pdbe.org/7qun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qun RCSB], [https://www.ebi.ac.uk/pdbsum/7qun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qun ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACPH_PIG ACPH_PIG] This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Sus scrofa domesticus]] | |||
[[Category: Harmat V]] | |||
[[Category: Jakli I]] | |||
[[Category: Kiss-Szeman AJ]] | |||
[[Category: Masiulis S]] | |||
[[Category: Menyhard KD]] | |||
[[Category: Perczel A]] | |||
[[Category: Straner P]] | |||
Revision as of 20:04, 16 November 2022
CryoEM structure of mammalian AAP in complex with Meropenem
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