8ewh: Difference between revisions
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==Salmonella typhimurium GTPase BIPA== | |||
<StructureSection load='8ewh' size='340' side='right'caption='[[8ewh]], [[Resolution|resolution]] 2.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ewh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EWH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ewh OCA], [https://pdbe.org/8ewh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ewh RCSB], [https://www.ebi.ac.uk/pdbsum/8ewh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ewh ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Brown | == Function == | ||
[[Category: Robinson | [https://www.uniprot.org/uniprot/BIPA_SALTY BIPA_SALTY] A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA (By similarity). A ribosome-stimulated GTPase, GTPase activity increases 4 fold in the presence of 70S ribosomes. Bind to 70S ribosomes in the presence of GTP or its non-hydrolyzable analog GMPPNP; in the presence of ppGpp or under stress conditions it binds to 30S ribosomal subunits (PubMed:18621905, PubMed:19803466).[HAMAP-Rule:MF_00849]<ref>PMID:18621905</ref> <ref>PMID:19803466</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | |||
[[Category: Brown RS]] | |||
[[Category: Robinson VL]] | |||
[[Category: DeLivron MA]] | |||
Revision as of 20:18, 16 November 2022
Salmonella typhimurium GTPase BIPA
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