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==Crystal Structure of Iml3 from S. cerevisiae==
==Crystal Structure of Iml3 from S. cerevisiae==
<StructureSection load='4it3' size='340' side='right' caption='[[4it3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4it3' size='340' side='right'caption='[[4it3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4it3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IT3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IT3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4it3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IT3 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4je3|4je3]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4it3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4it3 OCA], [https://pdbe.org/4it3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4it3 RCSB], [https://www.ebi.ac.uk/pdbsum/4it3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4it3 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IML3, MCM19, YBR107C, YBR0836 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4it3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4it3 OCA], [http://pdbe.org/4it3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4it3 RCSB], [http://www.ebi.ac.uk/pdbsum/4it3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4it3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IML3_YEAST IML3_YEAST]] Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation.<ref>PMID:11361335</ref> <ref>PMID:15241623</ref>
[https://www.uniprot.org/uniprot/CENPL_YEAST CENPL_YEAST] Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:11361335</ref> <ref>PMID:15241623</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Harrison, S C]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Hinshaw, S M]]
[[Category: Harrison SC]]
[[Category: Beta sheet]]
[[Category: Hinshaw SM]]
[[Category: Cell cycle]]
[[Category: Chl4]]
[[Category: Kinetochore]]
[[Category: Nucleus]]
Retrieved from "https://proteopedia.org/4it3"