7tj3: Difference between revisions

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'''Unreleased structure'''


The entry 7tj3 is ON HOLD
==Crystal structure of a dihydrofolate reductase folA from Stenotrophomonas maltophilia bound to NADP and p218==
 
<StructureSection load='7tj3' size='340' side='right'caption='[[7tj3]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7tj3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Stenotrophomonas_maltophilia_K279a Stenotrophomonas maltophilia K279a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TJ3 FirstGlance]. <br>
Description: Crystal structure of a dihydrofolate reductase folA from Stenotrophomonas maltophilia bound to NADP and p218
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MMV:3-(2-{3-[(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)OXY]PROPOXY}PHENYL)PROPANOIC+ACID'>MMV</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tj3 OCA], [https://pdbe.org/7tj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tj3 RCSB], [https://www.ebi.ac.uk/pdbsum/7tj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tj3 ProSAT]</span></td></tr>
[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/B2FPG1_STRMK B2FPG1_STRMK] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Stenotrophomonas maltophilia K279a]]
Retrieved from "https://proteopedia.org/7tj3"