7xrr: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7xrr is ~~ON HOLD until Paper Publication~~

==Crystal structure of the human OX2R bound to the insomnia drug lemborexant.==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7xrr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XRR FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRK:(1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide'>NRK</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xrr OCA], [https://pdbe.org/7xrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xrr RCSB], [https://www.ebi.ac.uk/pdbsum/7xrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xrr ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Asada H]]

[[Category: Im D]]

[[Category: Iwata S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7xrr is ON HOLD  until Paper Publication
+==Crystal structure of the human OX2R bound to the insomnia drug lemborexant.==
+<StructureSection load='7xrr' size='340' side='right'caption='[[7xrr]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7xrr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XRR FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRK:(1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide'>NRK</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xrr OCA], [https://pdbe.org/7xrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xrr RCSB], [https://www.ebi.ac.uk/pdbsum/7xrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xrr ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Asada H]]
+[[Category: Im D]]
+[[Category: Iwata S]]