1a0m: Difference between revisions
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<StructureSection load='1a0m' size='340' side='right'caption='[[1a0m]], [[Resolution|resolution]] 1.10Å' scene=''> | <StructureSection load='1a0m' size='340' side='right'caption='[[1a0m]], [[Resolution|resolution]] 1.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A0M FirstGlance]. <br> | <table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_episcopatus Conus episcopatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A0M FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [https://pdbe.org/1a0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [https://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [https://pdbe.org/1a0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [https://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CA1A_CONEP CA1A_CONEP] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-3-beta-4/CHRNA3-CHRNB4 subunits.<ref>PMID:9624161</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Conus episcopatus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alewood | [[Category: Alewood PF]] | ||
[[Category: Blessing | [[Category: Blessing RH]] | ||
[[Category: Hu | [[Category: Hu S-H]] | ||
[[Category: Lewis | [[Category: Lewis RJ]] | ||
[[Category: Loughnan | [[Category: Loughnan M]] | ||
[[Category: Martin | [[Category: Martin JL]] | ||
[[Category: Miller | [[Category: Miller R]] | ||
[[Category: Weeks | [[Category: Weeks CM]] | ||
