4jqf: Difference between revisions
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==Structure of the C-terminal domain of human telomeric Stn1== | ==Structure of the C-terminal domain of human telomeric Stn1== | ||
<StructureSection load='4jqf' size='340' side='right' caption='[[4jqf]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4jqf' size='340' side='right'caption='[[4jqf]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jqf]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4jqf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JQF FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqf OCA], [https://pdbe.org/4jqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jqf RCSB], [https://www.ebi.ac.uk/pdbsum/4jqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jqf ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/STN1_HUMAN STN1_HUMAN] Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.<ref>PMID:19854130</ref> <ref>PMID:19648609</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Bryan | [[Category: Large Structures]] | ||
[[Category: Harkisheimer | [[Category: Bryan CF]] | ||
[[Category: Rice | [[Category: Harkisheimer M]] | ||
[[Category: Schultz | [[Category: Rice CT]] | ||
[[Category: Skordalakes | [[Category: Schultz D]] | ||
[[Category: Skordalakes E]] | |||