1j59: Difference between revisions
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'''CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE''' | '''CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE''' | ||
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==About this Structure== | ==About this Structure== | ||
1J59 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry | 1J59 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ber 1ber]. The following page contains interesting information on the relation of 1J59 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb48_1.html Catabolite Activator Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J59 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Parkinson, G.]] | [[Category: Parkinson, G.]] | ||
[[Category: Wilson, C.]] | [[Category: Wilson, C.]] | ||
[[Category: | [[Category: Gene-regulatory]] | ||
[[Category: | [[Category: Protein-dna complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:49:13 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 17:49, 2 May 2008
CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Overview
The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.
About this Structure
1J59 is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1ber. The following page contains interesting information on the relation of 1J59 with [Catabolite Activator Protein]. Full crystallographic information is available from OCA.
Reference
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface., Parkinson G, Wilson C, Gunasekera A, Ebright YW, Ebright RE, Berman HM, J Mol Biol. 1996 Jul 19;260(3):395-408. PMID:8757802 Page seeded by OCA on Fri May 2 20:49:13 2008
