4k5p: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[4k5p]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Plafq Plafq~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5P OCA]. For a guided tour on the structure components use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4K5P FirstGlance].

<table><tr><td colspan='2'>[[4k5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5P OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4K5P FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=1OS:[(R)-AMINO(4-CARBAMIMIDOYLPHENYL)METHYL]PHOSPHONIC+ACID'>1OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1OS:[(R)-AMINO(4-CARBAMIMIDOYLPHENYL)METHYL]PHOSPHONIC+ACID'>1OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4k5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5p OCA], [https://pdbe.org/4k5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5p RCSB], [https://www.ebi.ac.uk/pdbsum/4k5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5p ProSAT]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4k5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5p OCA], [~~http~~://pdbe.org/4k5p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4k5p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4k5p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5p ProSAT]</td></tr>

</table>

== Function ==

[~~[http~~://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>

[https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>

== Publication Abstract from PubMed ==

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</StructureSection>

[[Category: Large Structures]]

[[Category: ~~Plafq~~]]

[[Category: Plasmodium falciparum FcB1/Columbia]]

[[Category: McGowan, S]]

[[Category: McGowan S]]

~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~

~~[[Category: M1 alanyl-aminopeptidase]]~~

~~[[Category: Protease~~]]

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 <StructureSection load='4k5p' size='340' side='right'caption='[[4k5p]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4k5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafq Plafq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K5P FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4k5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K5P FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1OS:[(R)-AMINO(4-CARBAMIMIDOYLPHENYL)METHYL]PHOSPHONIC+ACID'>1OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1OS:[(R)-AMINO(4-CARBAMIMIDOYLPHENYL)METHYL]PHOSPHONIC+ACID'>1OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k5l|4k5l]], [[4k5m|4k5m]], [[4k5n|4k5n]], [[4k5o|4k5o]], [[4k3n|4k3n]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5p OCA], [https://pdbe.org/4k5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5p RCSB], [https://www.ebi.ac.uk/pdbsum/4k5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5p ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5p OCA], [http://pdbe.org/4k5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k5p RCSB], [http://www.ebi.ac.uk/pdbsum/4k5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5p ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
+[https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 27: / Line 26: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Plafq]]
+[[Category: Plasmodium falciparum FcB1/Columbia]]
-[[Category: McGowan, S]]
+[[Category: McGowan S]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: M1 alanyl-aminopeptidase]]
-[[Category: Protease]]