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==The crystal structure of premithramycin B in complex with MTMOIV, a baeyer-villiger monooxygenase from the mithramycin biosynthetic pathway in streptomyces argillaceus.==
==The crystal structure of premithramycin B in complex with MTMOIV, a baeyer-villiger monooxygenase from the mithramycin biosynthetic pathway in streptomyces argillaceus.==
<StructureSection load='4k5s' size='340' side='right' caption='[[4k5s]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4k5s' size='340' side='right'caption='[[4k5s]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k5s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_argillaceus"_routien "streptomyces argillaceus" routien]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K5S FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k5s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_argillaceus Streptomyces argillaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K5S FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PM0:PREMITHRAMYCIN+B'>PM0</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PM0:PREMITHRAMYCIN+B'>PM0</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k5r|4k5r]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5s OCA], [https://pdbe.org/4k5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5s RCSB], [https://www.ebi.ac.uk/pdbsum/4k5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5s ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtmOIV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=41951 "Streptomyces argillaceus" Routien])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5s OCA], [http://pdbe.org/4k5s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k5s RCSB], [http://www.ebi.ac.uk/pdbsum/4k5s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q194P4_STRAA Q194P4_STRAA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces argillaceus routien]]
[[Category: Large Structures]]
[[Category: Bosserman, M A]]
[[Category: Streptomyces argillaceus]]
[[Category: Buchanan, S K]]
[[Category: Bosserman MA]]
[[Category: Noinaj, N]]
[[Category: Buchanan SK]]
[[Category: Rohr, J]]
[[Category: Noinaj N]]
[[Category: Baeyer-villiger]]
[[Category: Rohr J]]
[[Category: Fad binding protein]]
[[Category: Flavin binding protein]]
[[Category: Mithramycin]]
[[Category: Oxidoreductase]]
[[Category: Oxygenase]]
[[Category: Rossmann fold]]

Revision as of 11:41, 30 November 2022

The crystal structure of premithramycin B in complex with MTMOIV, a baeyer-villiger monooxygenase from the mithramycin biosynthetic pathway in streptomyces argillaceus.

4k5s, resolution 1.90Å

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