4k6t: Difference between revisions

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==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0385==
==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0385==
<StructureSection load='4k6t' size='340' side='right' caption='[[4k6t]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4k6t' size='340' side='right'caption='[[4k6t]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k6t]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Adenovirus_type_37 Adenovirus type 37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6T FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k6t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D37 Human adenovirus D37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6T FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1P0:2,2,2-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIETHANOL'>1P0</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1P0:2,2,2-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIETHANOL'>1P0</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k6u|4k6u]], [[4k6v|4k6v]], [[4k6w|4k6w]], [[3n0i|3n0i]], [[3qnd|3qnd]], [[1uxe|1uxe]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6t OCA], [https://pdbe.org/4k6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6t RCSB], [https://www.ebi.ac.uk/pdbsum/4k6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6t ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=52275 Adenovirus type 37])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6t OCA], [http://pdbe.org/4k6t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k6t RCSB], [http://www.ebi.ac.uk/pdbsum/4k6t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q64823_9ADEN Q64823_9ADEN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenovirus type 37]]
[[Category: Human adenovirus D37]]
[[Category: Bauer, J]]
[[Category: Large Structures]]
[[Category: Stehle, T]]
[[Category: Bauer J]]
[[Category: Adenovirus]]
[[Category: Stehle T]]
[[Category: Carbohydrate mimic]]
[[Category: Fiber knob]]
[[Category: Multivalent ligand]]
[[Category: Protein carbohydrate interaction]]
[[Category: Sialic acid]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/4k6t"