4k7k: Difference between revisions

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==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation==
==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation==
<StructureSection load='4k7k' size='340' side='right' caption='[[4k7k]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
<StructureSection load='4k7k' size='340' side='right'caption='[[4k7k]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k7k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K7K FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7K FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cusC, ibeB, ylcB, b0572, JW0561 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7k OCA], [https://pdbe.org/4k7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7k RCSB], [https://www.ebi.ac.uk/pdbsum/4k7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7k OCA], [http://pdbe.org/4k7k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k7k RCSB], [http://www.ebi.ac.uk/pdbsum/4k7k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref>
[https://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Lei, H T]]
[[Category: Large Structures]]
[[Category: Su, C C]]
[[Category: Lei H-T]]
[[Category: Beta barrel]]
[[Category: Su C-C]]
[[Category: Membrane protein]]
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