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==Crystal Structure of MBP Fused Human SPLUNC1==
==Crystal Structure of MBP Fused Human SPLUNC1==
<StructureSection load='4keg' size='340' side='right' caption='[[4keg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4keg' size='340' side='right'caption='[[4keg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4keg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KEG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4keg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLUNC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4keg OCA], [https://pdbe.org/4keg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4keg RCSB], [https://www.ebi.ac.uk/pdbsum/4keg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4keg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4keg OCA], [http://pdbe.org/4keg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4keg RCSB], [http://www.ebi.ac.uk/pdbsum/4keg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4keg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.  
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/BPIA1_HUMAN BPIA1_HUMAN] May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways.<ref>PMID:11425234</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Escherichia coli]]
[[Category: Chu, H W]]
[[Category: Homo sapiens]]
[[Category: Ning, F]]
[[Category: Large Structures]]
[[Category: Niu, L]]
[[Category: Chu HW]]
[[Category: Wang, C]]
[[Category: Ning F]]
[[Category: Zhang, G]]
[[Category: Niu L]]
[[Category: Bpi fold]]
[[Category: Wang C]]
[[Category: Lipid binding]]
[[Category: Zhang G]]
[[Category: Lipid binding protein]]
[[Category: Secreted]]

Revision as of 11:54, 30 November 2022

Crystal Structure of MBP Fused Human SPLUNC1

4keg, resolution 2.50Å

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