7ulw: Difference between revisions

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'''Unreleased structure'''


The entry 7ulw is ON HOLD  until Paper Publication
==CryoEM structure of human LACTB filament==
 
<StructureSection load='7ulw' size='340' side='right'caption='[[7ulw]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7ulw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ULW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ULW FirstGlance]. <br>
Description:  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ulw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ulw OCA], [https://pdbe.org/7ulw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ulw RCSB], [https://www.ebi.ac.uk/pdbsum/7ulw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ulw ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/LACTB_HUMAN LACTB_HUMAN] Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (PubMed:28329758). It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (PubMed:28329758). Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758).<ref>PMID:28329758</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aydin H]]
[[Category: Bennett JA]]
[[Category: Steward LR]]
Retrieved from "https://proteopedia.org/7ulw"