2fm2: Difference between revisions

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<StructureSection load='2fm2' size='340' side='right'caption='[[2fm2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2fm2' size='340' side='right'caption='[[2fm2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fm2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FM2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fm2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C] and [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FM2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BC:TERT-BUTYL+[(1S)-1-({(1R,2S,5S)-2-[(3S,10S)-3-(CYCLOPROPYLMETHYL)-12-METHYL-4,5,8,11-TETRAOXO-10-PHENYL-2,6,9,12-TETRAAZATRIDECAN-1-OYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEX-3-YL}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE'>3BC</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BC:TERT-BUTYL+[(1S)-1-({(1R,2S,5S)-2-[(3S,10S)-3-(CYCLOPROPYLMETHYL)-12-METHYL-4,5,8,11-TETRAOXO-10-PHENYL-2,6,9,12-TETRAAZATRIDECAN-1+-OYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEX-3-YL}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE'>3BC</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1a1r|1a1r]], [[1n1l|1n1l]], [[1rtl|1rtl]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS polyprotein ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11103 9HEPC])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fm2 OCA], [https://pdbe.org/2fm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fm2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fm2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fm2 OCA], [https://pdbe.org/2fm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fm2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fm2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9ELS8_9HEPC Q9ELS8_9HEPC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hepacivirus C]]
[[Category: Hepatitis C virus genotype 1a]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bogen, S L]]
[[Category: Bogen SL]]
[[Category: Bourne, N]]
[[Category: Bourne N]]
[[Category: Chase, R]]
[[Category: Chase R]]
[[Category: Chen, T]]
[[Category: Chen T]]
[[Category: Lemon, S M]]
[[Category: Lemon SM]]
[[Category: Malcolm, B A]]
[[Category: Malcolm BA]]
[[Category: Njoroge, F G]]
[[Category: Njoroge FG]]
[[Category: Prongay, A]]
[[Category: Prongay A]]
[[Category: Pyles, R B]]
[[Category: Pyles RB]]
[[Category: Saksena, A K]]
[[Category: Saksena AK]]
[[Category: Skelton, A]]
[[Category: Skelton A]]
[[Category: Tong, X]]
[[Category: Tong X]]
[[Category: Veselenak, R L]]
[[Category: Veselenak RL]]
[[Category: Yi, M]]
[[Category: Yi M]]
[[Category: Hcv]]
[[Category: Hepatitis c virus]]
[[Category: Hydrolase]]
[[Category: Ketoamide inhibitor]]
[[Category: Ns3/4a protease]]
Retrieved from "https://proteopedia.org/2fm2"