4ksc: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 3: Line 3:
<StructureSection load='4ksc' size='340' side='right'caption='[[4ksc]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<StructureSection load='4ksc' size='340' side='right'caption='[[4ksc]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ksc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KSC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ksc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KSC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ksb|4ksb]], [[4ksd|4ksd]], [[4lsg|4lsg]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ksc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ksc OCA], [https://pdbe.org/4ksc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ksc RCSB], [https://www.ebi.ac.uk/pdbsum/4ksc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ksc ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ksc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ksc OCA], [http://pdbe.org/4ksc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ksc RCSB], [http://www.ebi.ac.uk/pdbsum/4ksc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ksc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 22:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Xenobiotic-transporting ATPase]]
[[Category: Caya A]]
[[Category: Caya, A]]
[[Category: Chang G]]
[[Category: Chang, G]]
[[Category: Cregger C]]
[[Category: Cregger, C]]
[[Category: Doshi R]]
[[Category: Doshi, R]]
[[Category: Falson P]]
[[Category: Falson, P]]
[[Category: Govaerts C]]
[[Category: Govaerts, C]]
[[Category: Grimard V]]
[[Category: Grimard, V]]
[[Category: Lee C-W]]
[[Category: Lee, C W]]
[[Category: Martinez L]]
[[Category: Martinez, L]]
[[Category: Pardon E]]
[[Category: Pardon, E]]
[[Category: Steyaert J]]
[[Category: Steyaert, J]]
[[Category: Swartz DJ]]
[[Category: Swartz, D J]]
[[Category: Szewczyk P]]
[[Category: Szewczyk, P]]
[[Category: Urbatsch I]]
[[Category: Urbatsch, I]]
[[Category: Villaluz M]]
[[Category: Villaluz, M]]
[[Category: Ward A]]
[[Category: Ward, A]]
[[Category: Atp binding]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Transport protein]]
[[Category: Transporter]]
Retrieved from "https://proteopedia.org/4ksc"