4kyw: Difference between revisions

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==Restriction endonuclease DPNI in complex with two DNA molecules==
==Restriction endonuclease DPNI in complex with two DNA molecules==
<StructureSection load='4kyw' size='340' side='right' caption='[[4kyw]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='4kyw' size='340' side='right'caption='[[4kyw]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kyw]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KYW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kyw]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KYW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6MA:N6-METHYL-DEOXY-ADENOSINE-5-MONOPHOSPHATE'>6MA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6MA:N6-METHYL-DEOXY-ADENOSINE-5-MONOPHOSPHATE'>6MA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kyw OCA], [https://pdbe.org/4kyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kyw RCSB], [https://www.ebi.ac.uk/pdbsum/4kyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kyw ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4esj|4esj]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dpnC, spr1665, SP_1850 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kyw OCA], [http://pdbe.org/4kyw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kyw RCSB], [http://www.ebi.ac.uk/pdbsum/4kyw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kyw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/T2D1_STRPN T2D1_STRPN]] Recognizes the double-stranded and methylated sequence G(Me)ATC and cleaves after A-2.  
[https://www.uniprot.org/uniprot/T2D1_STRPN T2D1_STRPN] Recognizes the double-stranded and methylated sequence G(Me)ATC and cleaves after A-2.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Strpn]]
[[Category: Large Structures]]
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Bochtler, M]]
[[Category: Bochtler M]]
[[Category: Bujnicki, J M]]
[[Category: Bujnicki JM]]
[[Category: Czapinska, H]]
[[Category: Czapinska H]]
[[Category: Mierzejewska, K]]
[[Category: Mierzejewska K]]
[[Category: Siwek, W]]
[[Category: Siwek W]]
[[Category: Skowronek, K]]
[[Category: Skowronek K]]
[[Category: Dna binding]]
[[Category: Dpni]]
[[Category: Hydrolase-dna complex]]
[[Category: Methylation dependent]]
[[Category: N6-methyladenine]]
[[Category: Restriction endonuclease]]
[[Category: Restriction endonuclease-dna complex]]
[[Category: Restriction enzyme]]
[[Category: Type iie]]
[[Category: Type iim]]
[[Category: Winged helix domain]]