4l6y: Difference between revisions

<StructureSection load='4l6y' size='340' side='right'caption='[[4l6y]], [[Resolution|resolution]] 3.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[4l6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L6Y FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6y OCA], [https://pdbe.org/4l6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l6y RCSB], [https://www.ebi.ac.uk/pdbsum/4l6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6y ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PRC1_HUMAN PRC1_HUMAN] Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.<ref>PMID:9885575</ref> <ref>PMID:12082078</ref> <ref>PMID:15297875</ref> <ref>PMID:15625105</ref> <ref>PMID:16431929</ref> <ref>PMID:19468300</ref> <ref>PMID:20691902</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Darst SA]]

[[Category: Kapoor TM]]

[[Category: Subramanian R]]

[[Category: Tan L]]

[[Category: Ti S]]