Sandbox Reserved 1739: Difference between revisions
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== Function == | == Function == | ||
HCV is most closely related to the | HCV is most closely related to the ''Flaviviridae'' family. These viruses have a NS3 serine protease that is necessary for replication, but it is not known why. HCV also has a NS2-3 serine protease that executes ''cis'' cleavage at the 2/3 site and is autocatalytic, unlike other RNA viruses that just utilize the NS3 serine protease (2). | ||
The function of Hepatitis C primase is to build the viral capsid. The viral capsid is built by forming alpha helices in areas with bactericide, and forming aggregates in areas that lack them. Assembly happens from interactions between dimers and endoplasmic reticulum, along with other oligomers, proteins, and lipid droplets. The viral capsid and two glycoproteins make up the genome (1). | The function of Hepatitis C primase is to build the viral capsid. The viral capsid is built by forming alpha helices in areas with bactericide, and forming aggregates in areas that lack them. Assembly happens from interactions between dimers and endoplasmic reticulum, along with other oligomers, proteins, and lipid droplets. The viral capsid and two glycoproteins make up the genome (1). | ||
