Sandbox Reserved 1757: Difference between revisions
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== Function of your protein == | == Function of your protein == | ||
The enzyme acts as a catalyst for an elimination reaction removing the 3-phosphate group from mevalonate 3,5-biphosphate and decarboxylizes the substrate. My protein is an enzyme that catalyzes a reaction as referenced in the first sentence of my article “Mevalonate 3,5-bisphosphate decarboxylase is involved in the recently discovered Thermoplasma-type mevalonate pathway. The enzyme catalyzes the elimination of the 3- phosphate group from mevalonate 3,5-bisphosphate as well as concomitant decarboxylation of the substrate.” | |||
== Biological relevance and broader implications == | == Biological relevance and broader implications == | ||
== Important amino acids== | == Important amino acids== | ||
The article only really talks about how the ligand, like a fatty acid, lacks an ATP binding site. It also talks about the necessity of the ligand being amphipathic as there are hydrophilic and hydrophobic charges found in the binding site. | |||
== Structural highlights == | |||
The protein is a dimer that contains 14 helices and 15 beta sheets per linked molecule. The ARG 148 forms hydrogen bonds that allow it to pair with Oleic Acid, the protein’s ligand. Protein also requires H2O to be present in order to bind its <scene name='93/934001/Ligand/1'>ligand</scene>. I found it really interesting that the protein only actually attaches to the ligand via small interaction between ARG 148 and water molecules. | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
