1d59

CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA

spinqualitylabelsall models 1d59, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1d59 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility. Crystal structure of four-stranded Oxytricha telomeric DNA.,Kang C, Zhang X, Ratliff R, Moyzis R, Rich A Nature. 1992 Mar 12;356(6365):126-31. PMID:1545863 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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