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==Identifying ligand binding hot spots in proteins using brominated fragments==
==Identifying ligand binding hot spots in proteins using brominated fragments==
<StructureSection load='4lbw' size='340' side='right' caption='[[4lbw]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='4lbw' size='340' side='right'caption='[[4lbw]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lbw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LBW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lbw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LBW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h9g|4h9g]], [[4lbv|4lbv]], [[4lby|4lby]], [[4lbz|4lbz]], [[4lc0|4lc0]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbw OCA], [https://pdbe.org/4lbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lbw RCSB], [https://www.ebi.ac.uk/pdbsum/4lbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lbw ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tuf, tufA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbw OCA], [http://pdbe.org/4lbw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lbw RCSB], [http://www.ebi.ac.uk/pdbsum/4lbw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lbw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EFTU1_THETH EFTU1_THETH]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.  
[https://www.uniprot.org/uniprot/EFTU1_THETH EFTU1_THETH] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Elongation factor|Elongation factor]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
[[Category: Large Structures]]
[[Category: Groftehauge, M K]]
[[Category: Thermus thermophilus]]
[[Category: Morth, J P]]
[[Category: Groftehauge MK]]
[[Category: Nissen, P]]
[[Category: Morth JP]]
[[Category: Skrydstrup, T]]
[[Category: Nissen P]]
[[Category: Taaning, R]]
[[Category: Skrydstrup T]]
[[Category: Therkelsen, M]]
[[Category: Taaning R]]
[[Category: Gtpase]]
[[Category: Therkelsen M]]
[[Category: Plant protein]]
[[Category: Protein binding]]

Revision as of 10:50, 14 December 2022

Identifying ligand binding hot spots in proteins using brominated fragments

4lbw, resolution 1.74Å

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