4lli: Difference between revisions

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==Crystal Structure of human Myosin 5a globular domain==
==Crystal Structure of human Myosin 5a globular domain==
<StructureSection load='4lli' size='340' side='right' caption='[[4lli]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4lli' size='340' side='right'caption='[[4lli]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LLI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLI FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lnz|4lnz]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lli OCA], [https://pdbe.org/4lli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lli RCSB], [https://www.ebi.ac.uk/pdbsum/4lli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lli ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYH12, MYO5A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lli OCA], [http://pdbe.org/4lli PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lli RCSB], [http://www.ebi.ac.uk/pdbsum/4lli PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lli ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref>
[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4lli" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4lli" style="background-color:#fffaf0;"></div>
==See Also==
*[[Myosin|Myosin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Niessing, D]]
[[Category: Large Structures]]
[[Category: Velvarska, H]]
[[Category: Niessing D]]
[[Category: Dilute domain]]
[[Category: Velvarska H]]
[[Category: Globular tail]]
[[Category: Motor protein]]
[[Category: Type v myosin]]