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==Crystal structure of glyoxalase III (Orf 19.251) from Candida albicans==
==Crystal structure of glyoxalase III (Orf 19.251) from Candida albicans==
<StructureSection load='4lru' size='340' side='right' caption='[[4lru]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4lru' size='340' side='right'caption='[[4lru]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lru]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canal Canal]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LRU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lru]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LRU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CaO19.7882, Orf 19.251, orf19.7882 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237561 CANAL])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lru OCA], [https://pdbe.org/4lru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lru RCSB], [https://www.ebi.ac.uk/pdbsum/4lru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lru ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-lactate_dehydratase D-lactate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.130 4.2.1.130] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lru OCA], [http://pdbe.org/4lru PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lru RCSB], [http://www.ebi.ac.uk/pdbsum/4lru PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lru ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HSP31_CANAL HSP31_CANAL] Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. Selective for MG, does not use glyoxal as substrate. Plays a role in detoxifying endogenously produced MG, particularly when glycerol is the principal carbon source (PubMed:24302734). Important for viability in stationary phase (By similarity).[UniProtKB:Q04432]<ref>PMID:24302734</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Glyoxalase|Glyoxalase]]
*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Canal]]
[[Category: Candida albicans SC5314]]
[[Category: D-lactate dehydratase]]
[[Category: Large Structures]]
[[Category: Hasim, S]]
[[Category: Hasim S]]
[[Category: Hussin, N A]]
[[Category: Hussin NA]]
[[Category: Nickerson, K W]]
[[Category: Nickerson KW]]
[[Category: Wilson, M A]]
[[Category: Wilson MA]]
[[Category: Dj-1 superfamily]]
[[Category: Lyase]]
Retrieved from "https://proteopedia.org/4lru"