8hg1: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 8hg1 is ~~ON HOLD until Paper Publication~~

==The structure of MPXV polymerase holoenzyme in replicating state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8hg1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HG1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HG1 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hg1 OCA], [https://pdbe.org/8hg1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hg1 RCSB], [https://www.ebi.ac.uk/pdbsum/8hg1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hg1 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/Q5IXS4_MONPV Q5IXS4_MONPV] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.[ARBA:ARBA00025092]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Monkeypox virus]]

[[Category: Gao F]]

[[Category: Kuai L]]

[[Category: Peng Q]]

[[Category: Qi JX]]

[[Category: Shi Y]]

[[Category: Wang H]]

[[Category: Xie YF]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8hg1 is ON HOLD  until Paper Publication
+==The structure of MPXV polymerase holoenzyme in replicating state==
+<StructureSection load='8hg1' size='340' side='right'caption='[[8hg1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hg1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HG1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HG1 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hg1 OCA], [https://pdbe.org/8hg1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hg1 RCSB], [https://www.ebi.ac.uk/pdbsum/8hg1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hg1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q5IXS4_MONPV Q5IXS4_MONPV] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.[ARBA:ARBA00025092]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Monkeypox virus]]
+[[Category: Gao F]]
+[[Category: Kuai L]]
+[[Category: Peng Q]]
+[[Category: Qi JX]]
+[[Category: Shi Y]]
+[[Category: Wang H]]
+[[Category: Xie YF]]