1k99: Difference between revisions

Line 1:

==Solution Structure of the first HMG box in human Upstream binding factor==

== Structural highlights ==

<table><tr><td colspan='2'>[[1k99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K99 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=1K99 FirstGlance].

<table><tr><td colspan='2'>[[1k99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K99 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=1K99 FirstGlance].

</td></tr><tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">hUBF(103-192) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=1k99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k99 OCA], [https://pdbe.org/1k99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k99 RCSB], [https://www.ebi.ac.uk/pdbsum/1k99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k99 ProSAT]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=1k99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k99 OCA], [https://pdbe.org/1k99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k99 RCSB], [https://www.ebi.ac.uk/pdbsum/1k99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k99 ProSAT]</td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/UBF1_HUMAN UBF1_HUMAN]] Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.<ref>PMID:7982918</ref>

[https://www.uniprot.org/uniprot/UBF1_HUMAN UBF1_HUMAN] Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.<ref>PMID:7982918</ref>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Line 32:

Line 31:

__TOC__

</StructureSection>

[[Category: ~~Human~~]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Shi, Y]]

[[Category: Shi Y]]

[[Category: Wu, J]]

[[Category: Wu J]]

[[Category: Xu, Y]]

[[Category: Xu Y]]

[[Category: Yang, W]]

[[Category: Yang W]]

~~[[Category: Alpha-helix]]~~

~~[[Category: Dna binding protein]]~~

~~[[Category: L-shape~~]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
 ==Solution Structure of the first HMG box in human Upstream binding factor==
-<StructureSection load='1k99' size='340' side='right'caption='[[1k99]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='1k99' size='340' side='right'caption='[[1k99]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1k99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K99 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1k99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K99 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hUBF(103-192) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k99 OCA], [https://pdbe.org/1k99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k99 RCSB], [https://www.ebi.ac.uk/pdbsum/1k99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k99 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k99 OCA], [https://pdbe.org/1k99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k99 RCSB], [https://www.ebi.ac.uk/pdbsum/1k99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k99 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/UBF1_HUMAN UBF1_HUMAN]] Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.<ref>PMID:7982918</ref>
+[https://www.uniprot.org/uniprot/UBF1_HUMAN UBF1_HUMAN] Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.<ref>PMID:7982918</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 32: / Line 31: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Shi, Y]]
+[[Category: Shi Y]]
-[[Category: Wu, J]]
+[[Category: Wu J]]
-[[Category: Xu, Y]]
+[[Category: Xu Y]]
-[[Category: Yang, W]]
+[[Category: Yang W]]
-[[Category: Alpha-helix]]
-[[Category: Dna binding protein]]
-[[Category: L-shape]]