1kql: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1kql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQL FirstGlance]. <br>

<table><tr><td colspan='2'>[[1kql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQL FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kql OCA], [https://pdbe.org/1kql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kql RCSB], [https://www.ebi.ac.uk/pdbsum/1kql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kql ProSAT]</span></td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.

[https://www.uniprot.org/uniprot/TPM1_RAT TPM1_RAT] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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__TOC__

</StructureSection>

~~[[Category: Buffalo rat]]~~

[[Category: Large Structures]]

[[Category: ~~Brown, J H~~]]

[[Category: Rattus norvegicus]]

[[Category: ~~Cohen, C~~]]

[[Category: Saccharomyces cerevisiae]]

[[Category: ~~Li, Y~~]]

[[Category: Brown JH]]

[[Category: ~~Mui, S~~]]

[[Category: Cohen C]]

[[Category: ~~Reshetnikova, L~~]]

[[Category: Li Y]]

[[Category: ~~Strand, J~~]]

[[Category: Mui S]]

[[Category: ~~Tobacman,~~ L S]]

[[Category: Reshetnikova L]]

[[Category: ~~Coiled coil~~]]

[[Category: Strand J]]

[[Category: ~~Contractile protein]]~~

[[Category: Tobacman LS]]

~~[[Category: Four-helix bundle]]~~

~~[[Category: Muscle regulation]]~~

~~[[Category: Thin filament]]~~

~~[[Category: Tropomyosin~~]]

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@@ Line 3: / Line 3: @@
 <StructureSection load='1kql' size='340' side='right'caption='[[1kql]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1kql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1kql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQL FirstGlance]. <br>
 </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kql OCA], [https://pdbe.org/1kql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kql RCSB], [https://www.ebi.ac.uk/pdbsum/1kql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kql ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
+[https://www.uniprot.org/uniprot/TPM1_RAT TPM1_RAT] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 35: / Line 35: @@
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
 [[Category: Large Structures]]
-[[Category: Brown, J H]]
+[[Category: Rattus norvegicus]]
-[[Category: Cohen, C]]
+[[Category: Saccharomyces cerevisiae]]
-[[Category: Li, Y]]
+[[Category: Brown JH]]
-[[Category: Mui, S]]
+[[Category: Cohen C]]
-[[Category: Reshetnikova, L]]
+[[Category: Li Y]]
-[[Category: Strand, J]]
+[[Category: Mui S]]
-[[Category: Tobacman, L S]]
+[[Category: Reshetnikova L]]
-[[Category: Coiled coil]]
+[[Category: Strand J]]
-[[Category: Contractile protein]]
+[[Category: Tobacman LS]]
-[[Category: Four-helix bundle]]
-[[Category: Muscle regulation]]
-[[Category: Thin filament]]
-[[Category: Tropomyosin]]