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==Crystal structure of the S105A mutant of a C-C hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with substrate HOPDA==
==Crystal structure of the S105A mutant of a C-C hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with substrate HOPDA==
<StructureSection load='4lye' size='340' side='right' caption='[[4lye]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='4lye' size='340' side='right'caption='[[4lye]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lye]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphww Sphww]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LYE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LYE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lye]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizorhabdus_wittichii_RW1 Rhizorhabdus wittichii RW1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LYE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HPK:(3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE'>HPK</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPK:(3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE'>HPK</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lxg|4lxg]], [[4lyd|4lyd]], [[4lxh|4lxh]], [[4lxi|4lxi]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lye OCA], [https://pdbe.org/4lye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lye RCSB], [https://www.ebi.ac.uk/pdbsum/4lye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lye ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dxnB2, Swit_3055 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=392499 SPHWW])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2,6-dioxo-6-phenylhexa-3-enoate_hydrolase 2,6-dioxo-6-phenylhexa-3-enoate hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.8 3.7.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lye OCA], [http://pdbe.org/4lye PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lye RCSB], [http://www.ebi.ac.uk/pdbsum/4lye PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lye ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase]]
[[Category: Large Structures]]
[[Category: Sphww]]
[[Category: Rhizorhabdus wittichii RW1]]
[[Category: Bolin, J T]]
[[Category: Bolin JT]]
[[Category: Ghosh, S]]
[[Category: Ghosh S]]
[[Category: Alpha-beta hydrolase]]
[[Category: C-c bond hydrolase]]
[[Category: Dibenzo-p-dioxin degradation]]
[[Category: Dibenzofuran degradation]]
[[Category: Hydrolase]]
[[Category: Meta-cleavage product hydrolase]]

Revision as of 10:41, 21 December 2022

Crystal structure of the S105A mutant of a C-C hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with substrate HOPDA

4lye, resolution 2.33Å

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