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==Crystal structure of Aspergillus fumigatus protein farnesyltransferase binary complex with farnesyldiphosphate==
==Crystal structure of Aspergillus fumigatus protein farnesyltransferase binary complex with farnesyldiphosphate==
<StructureSection load='4mbg' size='340' side='right' caption='[[4mbg]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='4mbg' size='340' side='right'caption='[[4mbg]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mbg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspfu Aspfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MBG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mbg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MBG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l9p|4l9p]], [[4lnb|4lnb]], [[4lng|4lng]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mbg OCA], [https://pdbe.org/4mbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mbg RCSB], [https://www.ebi.ac.uk/pdbsum/4mbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mbg ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AFUA_4G07800 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=330879 ASPFU]), AFUA_4G10330 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=330879 ASPFU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_farnesyltransferase Protein farnesyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.58 2.5.1.58] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mbg OCA], [http://pdbe.org/4mbg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mbg RCSB], [http://www.ebi.ac.uk/pdbsum/4mbg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mbg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4WP27_ASPFU Q4WP27_ASPFU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Farnesyltransferase|Farnesyltransferase]]
*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspfu]]
[[Category: Aspergillus fumigatus Af293]]
[[Category: Protein farnesyltransferase]]
[[Category: Large Structures]]
[[Category: Beese, L S]]
[[Category: Beese LS]]
[[Category: Hast, M A]]
[[Category: Hast MA]]
[[Category: Mabanglo, M F]]
[[Category: Mabanglo MF]]
[[Category: Farnesyldiphosphate]]
[[Category: Farnesyltransferase inhibitor]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4mbg"