8bfh: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8bfh is ~~ON HOLD until Paper Publication~~

==CNOT11==

~~Authors~~: ~~Basquin~~, J., ~~Ozgur~~, S., ~~Conti~~, E.

== Structural highlights ==

<table><tr><td colspan='2'>[[8bfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BFH FirstGlance]. <br>

~~Description~~: ~~CNOT11~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bfh OCA], [https://pdbe.org/8bfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bfh RCSB], [https://www.ebi.ac.uk/pdbsum/8bfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bfh ProSAT]</span></td></tr>

[[Category: ~~Conti, E~~]]

</table>

[[Category: ~~Ozgur, S~~]]

== Function ==

[[Category: ~~Basquin, J~~]]

[https://www.uniprot.org/uniprot/CNO11_HUMAN CNO11_HUMAN] Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Basquin J]]

[[Category: Conti E]]

[[Category: Ozgur S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8bfh is ON HOLD  until Paper Publication
+==CNOT11==
+<StructureSection load='8bfh' size='340' side='right'caption='[[8bfh]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors: Basquin, J., Ozgur, S., Conti, E.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8bfh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BFH FirstGlance]. <br>
-Description: CNOT11
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bfh OCA], [https://pdbe.org/8bfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bfh RCSB], [https://www.ebi.ac.uk/pdbsum/8bfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bfh ProSAT]</span></td></tr>
-[[Category: Conti, E]]
+</table>
-[[Category: Ozgur, S]]
+== Function ==
-[[Category: Basquin, J]]
+[https://www.uniprot.org/uniprot/CNO11_HUMAN CNO11_HUMAN] Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Basquin J]]
+[[Category: Conti E]]
+[[Category: Ozgur S]]