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==1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis==
==1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis==
<StructureSection load='4mwa' size='340' side='right' caption='[[4mwa]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4mwa' size='340' side='right'caption='[[4mwa]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mwa]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_sterne) Bacillus anthracis (strain sterne)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MWA FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mwa]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Sterne Bacillus anthracis str. Sterne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MWA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwa OCA], [https://pdbe.org/4mwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mwa RCSB], [https://www.ebi.ac.uk/pdbsum/4mwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mwa ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS4180, BA_4502, GBAA_4502, gcpE, ispG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=260799 Bacillus anthracis (strain Sterne)])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate_synthase (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.7.1 1.17.7.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwa OCA], [http://pdbe.org/4mwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mwa RCSB], [http://www.ebi.ac.uk/pdbsum/4mwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mwa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPG_BACAN ISPG_BACAN]] Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity).  
[https://www.uniprot.org/uniprot/ISPG_BACAN ISPG_BACAN] Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity).
 
==See Also==
*[[IspG|IspG]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anderson, W F]]
[[Category: Bacillus anthracis str. Sterne]]
[[Category: Bishop, B]]
[[Category: Large Structures]]
[[Category: Brunzelle, J S]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Bishop B]]
[[Category: Cui, H]]
[[Category: Brunzelle JS]]
[[Category: Joachimiak, A]]
[[Category: Cui H]]
[[Category: Kwon, K]]
[[Category: Joachimiak A]]
[[Category: Maltseva, N]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Maltseva N]]
[[Category: Savchenko, A]]
[[Category: Minasov G]]
[[Category: Wawrzak, Z]]
[[Category: Savchenko A]]
[[Category: Xu, X]]
[[Category: Wawrzak Z]]
[[Category: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase]]
[[Category: Xu X]]
[[Category: Csgid]]
[[Category: Gcpe protein]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Oxidoreductase]]

Revision as of 10:14, 28 December 2022

1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis

4mwa, resolution 1.85Å

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