4n0i: Difference between revisions

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==Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine==
==Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine==
<StructureSection load='4n0i' size='340' side='right' caption='[[4n0i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4n0i' size='340' side='right'caption='[[4n0i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4n0i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N0I FirstGlance]. <br>
<table><tr><td colspan='2'>[[4n0i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N0I FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n0h|4n0h]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0i OCA], [https://pdbe.org/4n0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n0i RCSB], [https://www.ebi.ac.uk/pdbsum/4n0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n0i ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GatA, GEP6, HER2, LRC6, YMR293C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), GatB, PET112, YBL0724, YBL080C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), GatF, GTF1, YGR102C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0i OCA], [http://pdbe.org/4n0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n0i RCSB], [http://www.ebi.ac.uk/pdbsum/4n0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n0i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GATA_YEAST GATA_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling.<ref>PMID:19417106</ref> <ref>PMID:18667535</ref> [[http://www.uniprot.org/uniprot/GATF_YEAST GATF_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.<ref>PMID:19417106</ref> <ref>PMID:21799017</ref>  [[http://www.uniprot.org/uniprot/GATB_YEAST GATB_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<ref>PMID:19417106</ref> 
[https://www.uniprot.org/uniprot/GATA_YEAST GATA_YEAST] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling.<ref>PMID:19417106</ref> <ref>PMID:18667535</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4n0i" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4n0i" style="background-color:#fffaf0;"></div>
==See Also==
*[[Glutamyl-tRNA(Gln) amidotransferase|Glutamyl-tRNA(Gln) amidotransferase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Araiso, Y]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Ishitani, R]]
[[Category: Araiso Y]]
[[Category: Nureki, O]]
[[Category: Ishitani R]]
[[Category: Amidotransferase]]
[[Category: Nureki O]]
[[Category: Ligase]]
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