4n5x: Difference between revisions

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==Crystal structure of N-terminal calmodulin-like Calcium sensor of human mitochondrial ATP-Mg/Pi carrier SCaMC1==
==Crystal structure of N-terminal calmodulin-like Calcium sensor of human mitochondrial ATP-Mg/Pi carrier SCaMC1==
<StructureSection load='4n5x' size='340' side='right' caption='[[4n5x]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4n5x' size='340' side='right'caption='[[4n5x]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4n5x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N5X FirstGlance]. <br>
<table><tr><td colspan='2'>[[4n5x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC25A24, APC1, MCSC1, SCAMC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5x OCA], [https://pdbe.org/4n5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5x RCSB], [https://www.ebi.ac.uk/pdbsum/4n5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5x OCA], [http://pdbe.org/4n5x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n5x RCSB], [http://www.ebi.ac.uk/pdbsum/4n5x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SCMC1_HUMAN SCMC1_HUMAN]] Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.<ref>PMID:15123600</ref>
[https://www.uniprot.org/uniprot/SCMC1_HUMAN SCMC1_HUMAN] Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.<ref>PMID:15123600</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Bruschweiler, S]]
[[Category: Large Structures]]
[[Category: Chou, J]]
[[Category: Bruschweiler S]]
[[Category: Yang, Q]]
[[Category: Chou J]]
[[Category: Calcium sensor]]
[[Category: Yang Q]]
[[Category: Calcium-binding protein]]
[[Category: Calmodulin]]
[[Category: Mitochondrial inner membrane]]