7rb3: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7rb3 is ~~ON HOLD~~

==Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor==

~~Authors~~: ~~Deng~~, S., ~~Marmorstein~~, R.

== Structural highlights ==

<table><tr><td colspan='2'>[[7rb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RB3 FirstGlance]. <br>

~~Description~~: ~~Cryo~~-~~EM structure of human binary~~ NatC complex ~~with a Bisubstrate inhibitor~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rb3 OCA], [https://pdbe.org/7rb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rb3 RCSB], [https://www.ebi.ac.uk/pdbsum/7rb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rb3 ProSAT]</span></td></tr>

[[Category: Deng, S]]

</table>

[[Category: Marmorstein, R]]

== Function ==

[https://www.uniprot.org/uniprot/NAA35_HUMAN NAA35_HUMAN] Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.<ref>PMID:19398576</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Deng S]]

[[Category: Marmorstein R]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7rb3 is ON HOLD
+==Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor==
+<StructureSection load='7rb3' size='340' side='right'caption='[[7rb3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-Authors: Deng, S., Marmorstein, R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7rb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RB3 FirstGlance]. <br>
-Description: Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rb3 OCA], [https://pdbe.org/7rb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rb3 RCSB], [https://www.ebi.ac.uk/pdbsum/7rb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rb3 ProSAT]</span></td></tr>
-[[Category: Deng, S]]
+</table>
-[[Category: Marmorstein, R]]
+== Function ==
+[https://www.uniprot.org/uniprot/NAA35_HUMAN NAA35_HUMAN] Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.<ref>PMID:19398576</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Deng S]]
+[[Category: Marmorstein R]]