Potassium Channel: Difference between revisions
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'''Potassium channels''' (KCh) are subdivided into voltage-gated KCh and calcium-dependent KCh. The latter are subdivided into high- (BK, LKCa), intermediate- and small-conductance KCh (human SK1, rat SK2, SKCa). The T1 domain is a highly conserved N-terminal domain which is responsible for driving the tetramerization of the KCh α subunit. The inward rectifier KCh (IRK) passes current more easily in the inward direction. MthK is a calcium-dependent KCh from ''Methanobacterium thermoautrophicum''. | '''Potassium channels''' (KCh) are subdivided into voltage-gated KCh and calcium-dependent KCh. The latter are subdivided into high- (BK, LKCa), intermediate- and small-conductance KCh (human SK1, rat SK2, SKCa). The T1 domain is a highly conserved N-terminal domain which is responsible for driving the tetramerization of the KCh α subunit. The inward rectifier KCh (IRK) passes current more easily in the inward direction. KCh is activated by PIP2 [[Phosphatidylinositol bisphosphate (PIP2)]].MthK is a calcium-dependent KCh from ''Methanobacterium thermoautrophicum''. | ||
== 3D structures of Potassium Channels== | == 3D structures of Potassium Channels== | ||