7xc5: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~7xc5 is ON HOLD until Paper Publication~~

==Crystal structure of the ANK domain of CLPB==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7xc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XC5 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xc5 OCA], [https://pdbe.org/7xc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xc5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xc5 ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

== Disease ==

[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] 3-methylglutaconic aciduria type 7;Autosomal dominant severe congenital neutropenia. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6 (PubMed:31522117).<ref>PMID:31522117</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Gao N]]

[[Category: Lin J]]

[[Category: Liu Y]]

[[Category: Lu G]]

[[Category: Wu D]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7xc5 is ON HOLD  until Paper Publication
+==Crystal structure of the ANK domain of CLPB==
+<StructureSection load='7xc5' size='340' side='right'caption='[[7xc5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7xc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XC5 FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xc5 OCA], [https://pdbe.org/7xc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xc5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xc5 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] 3-methylglutaconic aciduria type 7;Autosomal dominant severe congenital neutropenia. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6 (PubMed:31522117).<ref>PMID:31522117</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Gao N]]
+[[Category: Lin J]]
+[[Category: Liu Y]]
+[[Category: Lu G]]
+[[Category: Wu D]]