8dk9: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''


The entry 8dk9 is ON HOLD  until 2024-01-05
==Sliding-clamp-DinX peptide==
 
<StructureSection load='8dk9' size='340' side='right'caption='[[8dk9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Kapur, M.K., Gray, O.J., Honzatko, R.H., Nelson, S.N.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8dk9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Mycolicibacterium_thermoresistibile Mycolicibacterium thermoresistibile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DK9 FirstGlance]. <br>
Description: Sliding-clamp-DinX peptide
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dk9 OCA], [https://pdbe.org/8dk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dk9 RCSB], [https://www.ebi.ac.uk/pdbsum/8dk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dk9 ProSAT]</span></td></tr>
[[Category: Honzatko, R.H]]
</table>
[[Category: Nelson, S.N]]
== Function ==
[[Category: Gray, O.J]]
[https://www.uniprot.org/uniprot/A0A100XCQ4_MYCTH A0A100XCQ4_MYCTH] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]
[[Category: Kapur, M.K]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycolicibacterium thermoresistibile]]
[[Category: Gray OJ]]
[[Category: Honzatko RH]]
[[Category: Kapur MK]]
[[Category: Nelson SN]]
Retrieved from "https://proteopedia.org/8dk9"