2kt5: Difference between revisions

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==RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide==
==RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide==
<StructureSection load='2kt5' size='340' side='right'caption='[[2kt5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kt5' size='340' side='right'caption='[[2kt5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hhv-1 Hhv-1] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KT5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KT5 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2f3j|2f3j]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kt5 OCA], [https://pdbe.org/2kt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2kt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kt5 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Refbp2, Ref2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kt5 OCA], [https://pdbe.org/2kt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2kt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kt5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ALRF2_MOUSE ALRF2_MOUSE]] Export adapter involved in spliced and unspliced mRNA nuclear export. Binds mRNA which is transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway); enhances NXF1-NXT1 RNA-binding activity.<ref>PMID:10786854</ref> <ref>PMID:11158589</ref> <ref>PMID:18364396</ref>
[https://www.uniprot.org/uniprot/ALRF2_MOUSE ALRF2_MOUSE] Export adapter involved in spliced and unspliced mRNA nuclear export. Binds mRNA which is transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway); enhances NXF1-NXT1 RNA-binding activity.<ref>PMID:10786854</ref> <ref>PMID:11158589</ref> <ref>PMID:18364396</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hhv-1]]
[[Category: Human alphaherpesvirus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Golovanov, A P]]
[[Category: Golovanov AP]]
[[Category: Hautbergue, G M]]
[[Category: Hautbergue GM]]
[[Category: Tunnicliffe, N B]]
[[Category: Tunnicliffe NB]]
[[Category: Wilson, S A]]
[[Category: Wilson SA]]
[[Category: Chaperone]]
[[Category: Mrna processing]]
[[Category: Mrna splicing]]
[[Category: Mrna transport]]
[[Category: Nucleus]]
[[Category: Ref icp27 hsv-1]]
[[Category: Rna binding protein - viral protein complex]]
[[Category: Rna-binding]]
[[Category: Spliceosome]]
[[Category: Transport]]