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==Solution structure of the S. cerevisiae H/ACA RNP protein Nhp2p==
==Solution structure of the S. cerevisiae H/ACA RNP protein Nhp2p==
<StructureSection load='2lbx' size='340' side='right'caption='[[2lbx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lbx' size='340' side='right'caption='[[2lbx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lbx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lbx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBX FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lbw|2lbw]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbx OCA], [https://pdbe.org/2lbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbx RCSB], [https://www.ebi.ac.uk/pdbsum/2lbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbx ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NHP2, YDL208W, D1045 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbx OCA], [https://pdbe.org/2lbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbx RCSB], [https://www.ebi.ac.uk/pdbsum/2lbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NHP2_YEAST NHP2_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth. Directly binds H/ACA snoRNAs.<ref>PMID:11433018</ref> <ref>PMID:9843512</ref> <ref>PMID:9848653</ref>
[https://www.uniprot.org/uniprot/NHP2_YEAST NHP2_YEAST] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth. Directly binds H/ACA snoRNAs.<ref>PMID:11433018</ref> <ref>PMID:9843512</ref> <ref>PMID:9848653</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chanfreau, G]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chim, N]]
[[Category: Chanfreau G]]
[[Category: Ding, Y]]
[[Category: Chim N]]
[[Category: Feigon, J]]
[[Category: Ding Y]]
[[Category: Fernandez, C F]]
[[Category: Feigon J]]
[[Category: Koo, B]]
[[Category: Fernandez CF]]
[[Category: Park, C]]
[[Category: Koo B]]
[[Category: L7ae]]
[[Category: Park C]]
[[Category: Rna binding protein]]
[[Category: Scarnp]]
[[Category: Snornp]]
Retrieved from "https://proteopedia.org/2lbx"