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==Bond length analysis of the PqqC Y175F mutant structure shows evidence for bound PQQ in the reduced form==
==Bond length analysis of the PqqC Y175F mutant structure shows evidence for bound PQQ in the reduced form==
<StructureSection load='4ny7' size='340' side='right' caption='[[4ny7]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
<StructureSection load='4ny7' size='340' side='right'caption='[[4ny7]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ny7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klep7 Klep7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NY7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ny7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_MGH_78578 Klebsiella pneumoniae subsp. pneumoniae MGH 78578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NY7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PQQ:PYRROLOQUINOLINE+QUINONE'>PQQ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PQQ:PYRROLOQUINOLINE+QUINONE'>PQQ</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hlx|3hlx]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ny7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ny7 OCA], [https://pdbe.org/4ny7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ny7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ny7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ny7 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pqqC, KPN78578_17810, KPN_01811 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272620 KLEP7])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrroloquinoline-quinone_synthase Pyrroloquinoline-quinone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.11 1.3.3.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ny7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ny7 OCA], [http://pdbe.org/4ny7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ny7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ny7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ny7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PQQC_KLEP7 PQQC_KLEP7]] Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.[HAMAP-Rule:MF_00654]  
[https://www.uniprot.org/uniprot/PQQC_KLEP7 PQQC_KLEP7] Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.[HAMAP-Rule:MF_00654]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Klep7]]
[[Category: Klebsiella pneumoniae subsp. pneumoniae MGH 78578]]
[[Category: Pyrroloquinoline-quinone synthase]]
[[Category: Large Structures]]
[[Category: Fisher, S J]]
[[Category: Fisher SJ]]
[[Category: Puehringer, S]]
[[Category: Puehringer S]]
[[Category: All helical]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/4ny7"