7wiu: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7wiu is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7wiu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIU FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wiu OCA], [https://pdbe.org/7wiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wiu RCSB], [https://www.ebi.ac.uk/pdbsum/7wiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wiu ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/IRTA_MYCTU IRTA_MYCTU] Part of the ABC transporter complex IrtAB involved in the import of iron-bound mycobactin (Fe-MBT) and carboxymycobactin (Fe-cMBT) (PubMed:16385031, PubMed:19948799) (By similarity). Mycobactins are then reduced by the siderophore interaction domain to facilitate iron release in the bacterial cell (By similarity). Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity). Required for replication in human macrophages and in mouse lungs (PubMed:16385031).[UniProtKB:G7CBF5]<ref>PMID:16385031</ref> <ref>PMID:19948799</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: Rao Z]]

[[Category: Sun S]]

[[Category: Yang H]]

[[Category: Zhang B]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7wiu is ON HOLD  until Paper Publication
+==Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state==
+<StructureSection load='7wiu' size='340' side='right'caption='[[7wiu]], [[Resolution|resolution]] 3.48&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7wiu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIU FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wiu OCA], [https://pdbe.org/7wiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wiu RCSB], [https://www.ebi.ac.uk/pdbsum/7wiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wiu ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IRTA_MYCTU IRTA_MYCTU] Part of the ABC transporter complex IrtAB involved in the import of iron-bound mycobactin (Fe-MBT) and carboxymycobactin (Fe-cMBT) (PubMed:16385031, PubMed:19948799) (By similarity). Mycobactins are then reduced by the siderophore interaction domain to facilitate iron release in the bacterial cell (By similarity). Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity). Required for replication in human macrophages and in mouse lungs (PubMed:16385031).[UniProtKB:G7CBF5]<ref>PMID:16385031</ref> <ref>PMID:19948799</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
+[[Category: Rao Z]]
+[[Category: Sun S]]
+[[Category: Yang H]]
+[[Category: Zhang B]]